Christine d'Ornano, daughter of Sisley founders Hubert and Isabelle d'Ornano, studied at Princeton University in the United States, then worked for over two years in the purchasing department at Saks Fifth Avenue in New York. She then joined the family business, first in Latin America, where she set up Sisley's Mexican subsidiary, then in the United Kingdom, where she established and managed the brand's UK and Irish subsidiary.
In 2017, she became Global Vice President of Sisley, with her brother Philippe d'Ornano as President. She works alongside him and their mother, Isabelle d'Ornano, on product development for Sisley and their hair care brand, Hair Rituel. She also oversees the group's Public Relations and Marketing departments.
In 2023, Philippe and Christine d'Ornano co-founded Neurae within the Sisley group, the first cosmetics brand entirely focused on neuroscience.